Severe mental retardation in 2 to 24-month-old children in Lahore, Pakistan : a prospective cohort study.
Severe mental retardation (developmental quotient (DQ)<50) was investigated in 1303 children from 2 to 24 months of age, born during 1984-87 in four population groups representing different socioeconomic levels in and around Lahore, Pakistan.
The incidence per 1000 live births was 22 in the periurban slum, 9 in the urban slum, 7 in the village and 4 in the upper middle class group.
The aetiology was prenatal in 79%, perinatal in 14% and untraceable in 7% of cases.
Down's syndrome was the most common cause of severe mental retardation (36%). Impairments were studied at 2 years of age.
Impairment of language was present in all, while locomotor dysfunction was seen in 89% of cases.
Epilepsy and cerebral palsy were each present in 22% of cases.
Mortality among these severely mentally retarded children was 36%.
Mots-clés Pascal : Arriération mentale, Enfant, Homme, Pakistan, Asie, Epidémiologie, Etude cohorte, Incidence, Etiologie, Déficience intellectuelle
Mots-clés Pascal anglais : Mental retardation, Child, Human, Pakistan, Asia, Epidemiology, Cohort study, Incidence, Etiology, Intellectual deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0246110
Code Inist : 002B17A01. Création : 09/06/1995.