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  1. Diverticulosis : a primary cause of life-threatening complications in rheumatoid arthritis.

    Article - En anglais

    Objective 

    To assess the role of complicated diverticular disease as a cause of death in rheumatoid arthritis (RA).

    Methods 

    In 1989 there were in Finland 1,666 deaths in subjects entitled to specially reinbursed medication for RA under the nation wide sickness insurance scheme.

    A retrospective clinical study was performed on these cases.

    Results 

    In 12 subjects, four males and eight females, the underlying cause of death was diverticular disease ; the expected munber was two.

    The mean age at death was 74 years in males and 80 years in females.

    The duration of RA ranged from 4 to 22 years (mean 13 years).

    In none of these cases was the death connected in the death certificate to RA or its treatment, yet all the subjects had been taking antirheumatic medication, usually two or three different drugs, at the time of death.

    Conclusion 

    Complicated diverticular disease, probably related to antirheumatic medication, is a more important cause of death in patients with RA than is generally recognized.

    Mots-clés Pascal : Polyarthrite rhumatoïde, Homme, Diverticulose, Mortalité, Finlande, Europe, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune, Appareil digestif pathologie

    Mots-clés Pascal anglais : Rheumatoid arthritis, Human, Diverticulosis, Mortality, Finland, Europe, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease, Digestive diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0245836

    Code Inist : 002B15D. Création : 09/06/1995.