Assessment of internal dose from radionuclides : dosimetric and biokinetic models.
The uptake of a radionuclide and its retention in a source organ or tissue following its ingestion, inhalation or systemic administration is described by biokinetic models, which are sufficiently simple to facilitate estimates of equivalent organ doses for radiological protection purposes.
For the assessment of annual limits on intakes of radionuclides by workers, and of dose coefficients for intakes of radionuclides by members of the public and patients, the International Commission on Radiological Protection (ICRP) has developed biokinetic models for the uptake of radionuclides by the gastrointestinal and the respiratory tract as well as for the systemic behaviour of radionuclides and their elimination from the body.
The dosimetric and biokinetic models and data used for the assessments are described in detail.
Present results and future activities of the ICRP on secondary limits for internal exposure are briefly mentioned.
Mots-clés Pascal : Radioisotope, Exposition professionnelle, Toxicocinétique, Métabolisme, Homme, Médecine travail, Modèle compartimental, Dosimétrie, Age, Voie orale, Inhalation
Mots-clés Pascal anglais : Radioisotope, Occupational exposure, Toxicokinetics, Metabolism, Human, Occupational medicine, Compartmental model, Dosimetry, Age, Oral administration, Inhalation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0245334
Code Inist : 002A08F02. Création : 09/06/1995.