Abstract Objectives-To compare the usefulness of high resolution computed tomography (HRCT) with chest radiography (CR) in the diagnosis and assessment of severity of silicosis.
Methods-27 workers exposed to silica underwent CR, HRCT, and pulmonary function tests.
Two experienced readers independently evaluated CR by International Labour Office classification, and grouped the results into four categories.
HRCT categories of nodule profusion and the extent of emphysema were graded on a four point scale ; in 20 subjects the percentage distribution of lung densities were measured by HRCT.
Concordance between readers was higher for HRCT than for CR (K statistic=0.49 and 0.29 respectively).
There was poor concordance between CR and HRCT in the early stages of silicosis.
No significant difference in pulmonary function tests was found among different CR categories, but forced expiratory volume in one second (FEV1), maximal expiratory flow at 50% and 75% of FVC (MEF50, MEF75), and diffusion capacity significantly decreased with increasing HRCT categories.
Subjects with simple silicosis detected by HRCT had a lower FEV1 than subjects without silicosis, whereas subjects with conglomerated silicosis showed higher residual volume and functional residual capacity than subjects with simple silicosis.
Mots-clés Pascal : Silice, Poussière, Exposition professionnelle, Médecine travail, Homme, Silicose, Thorax, Radiographie, Tomographie, Capacité fonctionnelle, Etude comparative, Intérêt, Diagnostic, Appareil respiratoire pathologie, Poumon pathologie, Pneumoconiose, Maladie professionnelle, Dépistage
Mots-clés Pascal anglais : Silica, Dust, Occupational exposure, Occupational medicine, Human, Silicosis, Thorax, Radiography, Tomography, Functional capacity, Comparative study, Interest, Diagnosis, Respiratory disease, Lung disease, Pneumoconiosis, Occupational disease, Medical screening
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0244444
Code Inist : 002B03L05. Création : 09/06/1995.