To investigate associations between exposure to pot emissions (fluorides, sulphur dioxide) and mortality from chronic obstructive lung disease, coal tar pitch volatiles and mortality from diseases related to atherosclerosis, and carbon monoxide and mortality from ischaemic heart disease.
Methods-Mortality between 1962 to 1991 was investigated in a cohort of 1085 men hired by a Norwegian aluminium smelter between 1922 and 1975.
Associations between cumulative exposure and mortality were investigated through SMR analysis based on national mortality rates ; temporal relations were explored by considering exposures only within specific time windows.
Circulatory mortality was also investigated by Poisson regression analysis.
There were 501 deaths upsilon 471.3 expected in the cohort.
The excess was confined to short term workers and did not seem to be associated with exposures in the smelter.
Analysis of mortality among the 661 men with at least three years employment showed associations between cumulative exposure to tar 40 years before observation and atherosclerotic mortality (P=0.03), and between exposure to pot emissions 20-39 years before observation and mortality from chronic obstructive lung disease (P=0.06).
No association was found between exposure to carbon monoxide and mortality from ischaemic heart disease, but cerebrovascular mortality was associated with exposure to pot emissions (P=0.02).
Mots-clés Pascal : Aluminium, Industrie, Fonderie, Exposition professionnelle, Homme, Tumeur maligne, Appareil circulatoire pathologie, Appareil respiratoire pathologie, Médecine travail, Composé aromatique polycyclique, Fluorure, Carbone monoxyde, Goudron
Mots-clés Pascal anglais : Aluminium, Industry, Foundry, Occupational exposure, Human, Malignant tumor, Cardiovascular disease, Respiratory disease, Occupational medicine, Polycyclic aromatic compound, Fluorides, Carbon monoxide, Tar
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0244443
Code Inist : 002B03L05. Création : 09/06/1995.