Epidemiologic follow-up studies of breast augmentation patients : Silicone breast implants and long-term health effects.
Although hundreds of thousands of women in this country have had augmentation mammaplasty, little is known about long-term effects.
Clinical studies have documented a decreased ability to detect breast lesions in women with implants, leading to concerns regarding breast cancer risk.
There is also anecdotal evidence that implants might have effects on a variety of immune conditions.
More recently, concern over carcinogenic effects has heightened given findings that the polyurethane foam, used in a minority of implants to envelope silicone gel, contains chemicals linked to cancer in laboratory animals.
Only a few epidemiologic studies on long-term effects have been published, and all have had methodologic limitations, including the possibility of inappropriate comparison rates, limited and/or incomplete follow-up, absence of information on patients characteristics, and lack of specific information on types of implanted material.
Several case-control and cohort studies are currently underway which are attempting to overcome methodologic limitations of previous studies.
Past descriptive and analytic studies are reviewed.
In addition, ongoing follow-up efforts are discussed, with attention given to the methodologic adjuncts necessary for allowing valid assessments of long-term disease effects.
Mots-clés Pascal : Chirurgie plastique, Glande mammaire, Prothèse, Siloxane polymère, Complication, Long terme, Homme, Femelle, Etude longitudinale, Epidémiologie, Méthodologie
Mots-clés Pascal anglais : Plastic surgery, Mammary gland, Prosthesis, Siloxane polymer, Complication, Long term, Human, Female, Follow up study, Epidemiology, Methodology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0241299
Code Inist : 002B25K. Création : 09/06/1995.