We describe an innovative strategy to quantify risk of cancer associated with varying levels of exposure to chronic parasitic infection through the identification of asymptomatic cases of cholangiocarcinoma within a population-based survey of Opisthorchis viverrini infection.
Stool samples from 12,311 adults over age 24 years from 85 villages in northeast Thailand were examined for intensity of liver fluke infection.
People from varying egg count categories were selected for ultrasound examination to identify hepatobiliary disease.
Fifteen preclinical cases of cholangiocarcinoma were diagnosed from a total of 1,807 people based on ultrasonographic evidence with confirmation by endoscopy where possible.
Mots-clés Pascal : Trématodose, Helminthiase, Parasitose, Infection, Opisthorchis viverrini, Trematoda, Plathelmintha, Helmintha, Invertebrata, Homme, Epidémiologie, Epithélioma, Voie biliaire, Association, Prévalence, Echelon régional, Thaïlande, Asie, Tumeur maligne, Voie biliaire pathologie, Appareil digestif pathologie, Etude transversale
Mots-clés Pascal anglais : Trematod disease, Helminthiasis, Parasitosis, Infection, Opisthorchis viverrini, Trematoda, Plathelmintha, Helmintha, Invertebrata, Human, Epidemiology, Carcinoma, Biliary tract, Association, Prevalence, Regional scope, Thailand, Asia, Malignant tumor, Biliary tract disease, Digestive diseases, Cross sectional study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0240113
Code Inist : 002B13C01. Création : 09/06/1995.