The relationship between mammographic patterns and reproductive and menstrual factors was examined in 3640 Norwegian women, aged 40-56 years, participating in the Third Tromsö study conducted in 1986-87.
Epidemiological data were obtained from questionnaires.
The mammograms were categorised into five groups.
This categorisation is based on anatomic-mammographic correlations, following threedimensional (thick slice technique) histopathologic-mammographic comparisons, rather than simple pattern reading.
Patterns 1-3 were combined into a low-risk group and patterns 4 and 5 into a high-risk group for analysis.
Women who had more than four children were 90% less likely to have a high-risk pattern than nulliparous women (OR=0.09,95% CI 0.04-0.16) controlling for age, weight, height and menopausal status.
Furthermore, those who first gave birth over 34 years of age were more than twice as likely to have a high-risk pattern than those giving birth in their teens (OR=2.37,95% CI 1.23-4.56) adjusting for parity.
Among post-menopausal women, age at menarche was negatively (P for trend=0.015) and late age at menopause positively (P for trend=0.072) related to high-risk patterns.
Among premenopausal women, age at menarche was positively related to high-risk patterns (P for trend=0.001).
Also, menopausal status rather than age was associated with high-risk patterns.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Epidémiologie, Reproduction, Parité, Première menstruation, Ménopause, Exploration radiologique, Mammographie, Norvège, Europe, Homme, Glande mammaire pathologie, Radiodiagnostic
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Epidemiology, Reproduction, Parity, Menarche, Menopause, Radiologic investigation, Mammography, Norway, Europe, Human, Mammary gland diseases, Radiodiagnosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0228415
Code Inist : 002B20E02. Création : 09/06/1995.