Reproductive and menstrual factors in relation to mammographic parenchymal patterns among perimenopausal women.
The relationship between mammographic patterns and reproductive and menstrual factors was examined in 3640 Norwegian women, aged 40-56 years, participating in the Third Tromsö study conducted in 1986-87.
Epidemiological data were obtained from questionnaires.
The mammograms were categorised into five groups.
This categorisation is based on anatomic-mammographic correlations, following threedimensional (thick slice technique) histopathologic-mammographic comparisons, rather than simple pattern reading.
Patterns 1-3 were combined into a low-risk group and patterns 4 and 5 into a high-risk group for analysis.
Women who had more than four children were 90% less likely to have a high-risk pattern than nulliparous women (OR=0.09,95% CI 0.04-0.16) controlling for age, weight, height and menopausal status.
Furthermore, those who first gave birth over 34 years of age were more than twice as likely to have a high-risk pattern than those giving birth in their teens (OR=2.37,95% CI 1.23-4.56) adjusting for parity.
Among post-menopausal women, age at menarche was negatively (P for trend=0.015) and late age at menopause positively (P for trend=0.072) related to high-risk patterns.
Among premenopausal women, age at menarche was positively related to high-risk patterns (P for trend=0.001).
Also, menopausal status rather than age was associated with high-risk patterns.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Epidémiologie, Reproduction, Parité, Première menstruation, Ménopause, Exploration radiologique, Mammographie, Norvège, Europe, Homme, Glande mammaire pathologie, Radiodiagnostic
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Epidemiology, Reproduction, Parity, Menarche, Menopause, Radiologic investigation, Mammography, Norway, Europe, Human, Mammary gland diseases, Radiodiagnosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0228415
Code Inist : 002B20E02. Création : 09/06/1995.