Although heavy or long-term use of analgesics has been related to risk of renal cell cancer in several studies, evidence for such an association remains inconclusive.
In a population-based case-control study including 440 renal cell cancer cases, spouses of an additional 151 cases, and 691 controls, we assessed renal cell cancer risk associated with lifetime consumption among those who reported during in-person interviews regular (at least 2 or more times per week for 1 month or longer) use of analgesics.
Odds ratios (OR) were computed using logistic regression analyses.
No excess risk was associated with regular use of aspirin, acetaminophen, phenacetin or combinations of these agents, nor did risks rise with increasing cumulative intake of these analgesics.
Mots-clés Pascal : Hypernéphrome, Epithélioma, Homme, Epidémiologie, Facteur risque, Paracétamol, Phénacétine, Acétylsalicylique acide, Analgésique, Toxicité, Tumeur maligne, Rein pathologie, Appareil urinaire pathologie, Etude cas témoin
Mots-clés Pascal anglais : Grawitz tumor, Carcinoma, Human, Epidemiology, Risk factor, Analgesic, Toxicity, Malignant tumor, Renal disease, Urinary system disease, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0227278
Code Inist : 002B14D01. Création : 09/06/1995.