To evaluate the incidence of second malignant tumors in a cohort of subjects previously treated for childhood cancer, we analyzed data from the Off-Therapy Registry (OTR) of the Italian Association of Pediatric Hematology/Oncology, which collects information on children treated for Hodgkin's disease, non-Hodgkin's lymphoma, Wilms'tumor, acute lymphoblastic leukemia (ALL) and acute non-lymphatic leukemia and who had been removed from treatment in the absence of clinical signs of disease, i.e. the off-therapy stage.
Second malignant tumors (SMT), diagnosed before December 31,1988, were identified through a special enquiry to the 36 institutions cooperating in the registry.
Mots-clés Pascal : Hémopathie maligne, Tumeur maligne, Enfant, Homme, Nourrisson, Complication, Second cancer, Epidémiologie, Incidence, Etude multicentrique, Italie, Europe
Mots-clés Pascal anglais : Malignant hemopathy, Malignant tumor, Child, Human, Infant, Complication, Second cancer, Epidemiology, Incidence, Multicenter study, Italy, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0227255
Code Inist : 002B04B. Création : 09/06/1995.