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  1. Relations between antioxidant vitamins in adipose tissue, plasma, and diet.

    Article - En anglais

    For an evaluation of fat-soluble vitamin concentrations in adipose tissue as biomarkers of intake, estimates of usual intake of bêta-carotene, total vitamin A, and vitamin E (assessed by food frequency questionnaire) were compared with plasma and adipose tissue concentrations of bêta-carotene, retinol, and alpha-tocopherol, respectively.

    Data were collected in 1992 in the Netherlands for 85 healthy, nonsmoking volunteers aged 50-70 years (38 males and 47 females).

    For alpha-tocopherol, a significant age-and sex-adjusted partial correlation (r=0.24, p<0.05) was observed between adipose tissue levels and intake.

    For bêta-carotene, the partial r was 0.20.

    Adipose tissue retinol did not reflect intake (partial r=0.08).

    Correlations of adipose tissue vitamin levels with plasma vitamin levels were higher overall (r=0.34 for alpha-tocopherol, r=0.56 for bêta-carotene, and r=0.17 for retinol) than correlations with intake.

    Plasma concentrations of alpha-tocopherol, bêta-carotene, and retinol were not associated with dietary intake (partial r's were 0.05,0. 17, and - 0. 12, respectively).

    Pearson correlations of repeated measurements in adipose tissue (after 4 months) were 0.24 for retinol, 0.50 for bêta-carotene, and 0.78 for alpha-tocopherol.

    Adipose tissue bêta-carotene was shown to increase sixfold after 6 months'supplementation with 30 mg of bêta-carotene daily.

    Mots-clés Pascal : Consommation alimentaire, Antioxydant, Vitamine, Régime alimentaire enrichi, Homme, Epidémiologie, Marqueur biologique, Taux, Plasma sanguin, Tissu adipeux, Carotène, Rétinol, alpha-Tocophérol, Méthodologie, Nutrition

    Mots-clés Pascal anglais : Food intake, Antioxidant, Vitamin, Supplemented diet, Human, Epidemiology, Biological marker, Rate, Blood plasma, Adipose tissue, Carotene, Retinol, alpha-Tocopherol, Methodology, Nutrition

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0223881

    Code Inist : 002B29B. Création : 09/06/1995.