Coincident with the licensure of Haemophilus influenzae b confugate vaccines from 1987 to 1990, the incidence of meningitis and other invasive infections caused by H influenzae type b declined in Massachusetts children by 87% and 91% respectively.
By 1991, Neisseria meningitidis had replaced H influenzae b as the leading cause of bacterial meningitis, accounting for 57% of cases.
During the period 1984 through 1991, serogroup C displaced sero-group B as the most common cause of N meningitidis disease, with serogroups 14,6,19,18,4,23, and 9 causing 94.5% of infections for the development of additional polysaccharide-protein conjugate vaccines for the prevention of childhood infections.
Mots-clés Pascal : Bactériose, Infection, Epidémiologie, Enfant, Homme, Massachusetts, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Bacteriosis, Infection, Epidemiology, Child, Human, Massachusetts, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0220410
Code Inist : 002B05A02. Création : 09/06/1995.