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  1. A population-based serologic survey of immunity to tetanus in the United States.

    Article - En anglais


    Vaccination rates are frequently considered a surrogate measure of protection.

    To provide more accurate estimates, serum levels of antibody against tetanus were measured as part of the third National Health and Nutrition Examination Survey (NHANES III), which studied a representative sample of the civilian, noninstitutionalized population of the United States.


    We measured tetanus antitoxin using a solid-phase enzyme immunoassay in serum samples from 10,618 persons six years of age and older who were examined during phase 1 of NHANES III in 1988 to 1991.


    Overall, 69.7 percent of Americans six years of age and older had protective levels of tetanus antibodies (>0.15 IU per milliliter).

    The rate decreased from 87.7 percent among those 6 to 11 years of age to 27.8 percent among those 70 years of age or older.

    Among children 6 to 16 years of age, 82.2 percent had protective levels of tetanus antibodies, with little variation according to race or ethnicity.

    More men than women were immune (79.0 percent vs. 62.4 percent).

    Mexican Americans had a significantly lower rate of immunity (57.9 percent, P<0.05) than either non-Hispanic whites (72.7 percent) or non-Hispanic blacks (68.1 percent).

    Those with a history of military service, higher levels of education, or incomes above the poverty level were more likely to have protective antibody levels.

    Mots-clés Pascal : Tétanos, Bactériose, Infection, Prévention, Vaccination, Evaluation performance, Etats Unis, Amérique du Nord, Amérique, Homme

    Mots-clés Pascal anglais : Tetanus, Bacteriosis, Infection, Prevention, Vaccination, Performance evaluation, United States, North America, America, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0219256

    Code Inist : 002B05A02. Création : 09/06/1995.