In vivo XRF analysis of mercury : the relation between concentrations in the kidney and the urine.
The objective of this study was to determine the concentrations of mercury in organs of occupationally exposed workers using in viro x-ray fluorescence analysis.
Twenty mercury exposed workers and twelve occupationally unexposed referents participated in the study.
Their mercury levels in kidney, liver and thyroid were measured using a technique based on excitation with partly plane polarized photons.
The mercury levels in blood and urine were determined using atomic absorption spectrophotometry.
The detection limit for mercury in the kidney was exceeded in nine of the exposed workers, but in none of the referents.
The mean kidney mercury concentration (including estimates below the detection limits) was 24 mug g-1 in the exposed workers, and 1 mug g-1 in the referents.
The association between mercury in the kidney and in urine was statistically significant, but it was unclear whether the relation was linear.
The measurements on liver (n=10) and thyroid (n=8) in the exposed workers showed mercury levels below the detection limit.
The study shows that it is now possible to measure the mercury concentrations in kidneys of occupationally exposed persons, using in vivo x-ray fluorescence.
The estimated concentrations are in reasonable agreement with the limited human autopsy data, and the results of animal studies.
Mots-clés Pascal : Mercure, Exposition professionnelle, In vivo, Fluorescence RX, Rein, Foie, Thyroïde, Urine, Sang, Spectrophotométrie, Technique mesure, Précision mesure, Métal lourd, Appareil urinaire, Appareil digestif
Mots-clés Pascal anglais : Mercury, Occupational exposure, In vivo, X ray fluorescence, Kidney, Liver, Thyroid gland, Urine, Blood, Spectrophotometry, Measurement technique, Measurement accuracy, Heavy metal, Urinary system, Digestive system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0214457
Code Inist : 002B30B01A. Création : 09/06/1995.