In this study the long-term prognosis was analysed of all 462 consecutive female breast cancer patients who were diagnosed and carefully staged between 1970 and 1980 in a 600-bed community hospital in Eindhoven, south east Netherlands.
Follow-up of recurrence and causes of death was obtained until 1 January 1993.
Observed survival rates at 5,10 and 20 years were 66%, 45% and 32%, respectively, and the corresponding breast cancer-specific survival rates were 71%, 54% and 44%. The yearly risk for a recurrence of breast cancer after treatment steadily decreased from 10% the first year to 1% after 10 years.
In a multivariate survival analysis both tumour size and nodal status appeared to be equally important prognostic factors in the first 5 years after diagnosis.
After 5 years only tumour size had independent prognostic value, which was not significant any more after 10 years.
In patients with a tumour size ¾ 2 cm and without lymph node involvement at diagnosis, the risk for a recurrence was found to be negligible after 10 years.
Those patients may be considered cured, although a search for early diagnosis of a second primary breast cancer in this group is still advisable.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Homme, Pronostic, Long terme, Epidémiologie, Survie, Complication, Etude cohorte, Echelon local, Pays Bas, Europe, Glande mammaire pathologie, Facteur prédictif
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Human, Prognosis, Long term, Epidemiology, Survival, Complication, Cohort study, Local scope, Netherlands, Europe, Mammary gland diseases, Predictive factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0212909
Code Inist : 002B20E02. Création : 09/06/1995.