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  1. A non-invasive measure of photoageing.

    Article - En anglais


    Photoageing develops in skin due to chronic sun exposure and amethod of measuring photoageing would be useful in monitoring solar damage in populations, in studies of sun exposure as an aetiological agent, and in the evaluation of the effects of cosmetics and therapeutics.

    Methods of measuring photoageing include several invasive techniques as well as non-invasive techniques which are often difficult to use and have not been validated.

    The non-invasive measure of photoageing described here is a new method for grading silicone-rubber casts of the skin surface.

    This paper describes the development of the measure (named the sigma system) and compares its reliability and validity with the most widely-used similar measure (the Beagley and Gibson system).


    Useable punch biopsies and silicone-rubber casts were obtained from 82 subjects.

    Two random subgroups of silicone casts were created and the first subgroup was used for the development of the sigma system, while the second subgroup was used to test validity.

    All casts were graded twice using the sigma system and twice using the Beagley and Gibson system by two observers.

    The gradings of the second subgroup of casts were compared with the degree of photoageing seen on histological examination of the biopsies.

    Mots-clés Pascal : Vieillissement, Peau, Soleil, Méthode mesure, Evaluation performance, Fiabilité, Validation, Peau pathologie, Homme

    Mots-clés Pascal anglais : Ageing, Skin, Sun, Measurement method, Performance evaluation, Reliability, Validation, Skin disease, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0210727

    Code Inist : 002B24O01. Création : 09/06/1995.