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  1. Fulltext. Heroin use during methadone maintenance treatment : the importance of methadone dose and cocaine use.

    Article - En anglais



    The purpse of this study was to examine factors associated with heroin use during methadone maintenance treatment.


    Logistic regression statistical models were used to examine data obtained in a cross-sectional sample of 652 methadone patients.


    Heroin use duriong the 3 months prior to interview was shown to be greatest among (1) patients maintained on methadone dosages of less than 70 mg/day [OR]=2.1,95% confidence interval [CI]=1.3,3.4) and (2) paitents who used cocaine during treatment (adjusted OR=5.9,95% CI=3.8,9.1).

    These results were independent of treatment duration, treatment compliance, alcohol use, and socioeconomic factors.

    Cocaine users were more likely than nonusers of cocaine to use heroin at all methadone dosage levels.


    This study confirms and extends past research showing high-dose methadone maintenance to be important to heroin abstinence.

    Further investigation of the indenpent association between heroin use and cocaine use is needed.

    Mots-clés Pascal : Diamorphine, Toxicomanie, Méthadone, Efficacité traitement, Chimiothérapie, Posologie, Relation dose réponse, Récidive, Homme, Epidémiologie, New York, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Heroin, Drug addiction, Treatment efficiency, Chemotherapy, Posology, Dose activity relation, Relapse, Human, Epidemiology, New York, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0209111

    Code Inist : 002B03D. Création : 09/06/1995.