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  1. Fulltext. World war II : veteran male twins who are discordant for alcohol consumption : 24-year mortality.

    Article - En anglais


    The role of genetic and shared environmental influences in the assication of alcohol with mortality was studied by using the National Academy of Sciences-National Research Council World War II-veteran male twin registry.

    An epidemiologic questionnaire administered from 1967 through 1969 permitted identification of twin pairs discordant for alcohol consumption.

    The subsequent 24 years of mortality follow-up yielded data on time and cause of death.

    Analyzing the first or only death in drinking-discordant pairs, we observed 27 deaths in abstainer twins and 14 deaths in their light-to moderate-drinker cotwins (relative risk [RR]=1.93).

    Excess mortality in twin abstainers was also indicated for deaths from cardiovasculr diseases (RR=2.0) and other cuases of death excluding cancers (RR=3.2).

    The protective effect, however, of light to moderate drinking did not persist in twins who were smokers at baseline.

    Mots-clés Pascal : Alcoolisme, Mortalité, Jumeau, Homme, Déterminisme génétique, Epidémiologie, Facteur risque, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Alcoholism, Mortality, Twin, Human, Genetic inheritance, Epidemiology, Risk factor, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0208929

    Code Inist : 002B03F. Création : 09/06/1995.