While coronary heart disease (CHD) is a serious and often fatal disease the prognosis is variable and major effort has been invested in risk stratification.
The purpose of this study was to examine the relation between long-term prognosis and risk factors in different clinical categories of CHD.
A general population sample of 9141 men, aged 34-79 at entry into the study was divided into six groups with respect to manifestations of CHD at entry : I. Symptomatic infarction.
II. Silent or unrecognized infarction.
Angina pectoris with ischaemic changes on ECG.
IV. Angina without ischaemic changes.
V. Angina by Rose questionnaire but not confirmed by a physician.
VI. No manifestations of CHD.
The risk factor profile varied considerably between the different categories and by life-table analysis marked differences in survival were demonstrated between the groups.
The risk factors maintained their detrimental effects on prognosis in the presence of CHD.
Thus, age, serum total cholesterol, impaired glucose tolerance and smoking were found by Cox's regression to be statistically significant independent risk factors of CHD mortality among men having manifestations of CHD (groups I-V).
Mots-clés Pascal : Cardiopathie coronaire, Epidémiologie, Homme, Pronostic, Long terme, Facteur risque, Islande, Iles Atlantiques, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Coronary heart disease, Epidemiology, Human, Prognosis, Long term, Risk factor, Iceland, Atlantic Ocean Islands, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0208875
Code Inist : 002B12A03. Création : 09/06/1995.