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  1. Alcohol consumption and all-cause mortality.

    Article - En anglais

    Background

    Prospective studies of alcohol and mortality in middle-aged men almost universally find a U-shaped relationship between alcohol consumption and risk of mortality.

    This review demonstrates the extent to which different studies lead to different risk estimates, analyses the putative influence of abstention as a risk factor and uses available data to produce point and interval estimates of the consumption level apparently associated with minimum risk from two studies in the UK.

    Method

    Data from a number of studies are analysed by means of logistic-linear modelling, taking account of the possible influence of abstention as a special risk factor.

    Separate analysis of British data is performed.

    Results

    Logistic-linear modelling demonstrates large and highly significant differences between the studies considered in the relationship between alcohol consumption and all-cause mortality.

    The results support the identification of abstention as a special risk factor for mortality, but do not indicate that this alone explains the apparent U-shaped relationship.

    Separate analysis at two British studies indicates minimum risk of mortality in this population at a consumption level of about 26 (8.5 g) units of alcohol per week.

    Conclusions.

    Mots-clés Pascal : Consommation, Ethanol, Epidémiologie, Mortalité, Homme, Prospective, Royaume Uni, Europe

    Mots-clés Pascal anglais : Consumption, Ethanol, Epidemiology, Mortality, Human, Prospective, United Kingdom, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0208864

    Code Inist : 002B03F. Création : 09/06/1995.