Mesothelioma is closely related to exposure to asbestos, and mesothelioma mortality can be taken as an index of past exposure to asbestos in the population.
We analysed mesothelioma mortality since 1968 to assess the current state of the mesothelioma epidemic, and to predict its future course.
We found that rates of mesothelioma in men formed a clear pattern defined by age and date of birth.
Rates rose steeply with age showing a very similar pattern in all five-year birth cohorts.
By date of birth, rates increased from mid-1893 to mid-1948, and then fell.
Relative to the 1943-48 cohort, the risk for the 1948-53 cohort is 079 and for the 1953-58 cohort 0.48.
Despite these falls, if the age profile of rates for these cohorts follows the pattern of past cohorts, their predicted lifetime mesothelioma risks will be 1.3%, 1.0%, and 0.6%. Combining projections for all cohorts results in a peak of annual male mesothelioma deaths in about the year 2020 of between 2700 and 3300 deaths.
If diagnostic trend is responsible for a 20% growth in recorded cases every 5 years-an extreme but arguable case-and if this trend has now ceased, the peak of annual male deaths will be reduced to 1300, reached around the year 2010.
Analysis of occupations recorded on death certificates indicate that building workers, especially plumbers and gas fitters, carpenters and electricians are the largest high-risk group.
Mots-clés Pascal : Appareil digestif pathologie, Appareil respiratoire pathologie, Tumeur, Complication, Mortalité, Homme, Mésothéliome, Asbestose, Rétrospective, Prédiction, Angleterre, Grande Bretagne, Royaume Uni, Europe
Mots-clés Pascal anglais : Digestive diseases, Respiratory disease, Tumor, Complication, Mortality, Human, Mesothelioma, Asbestosis, Retrospective, Prediction, England, Great Britain, United Kingdom, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0207540
Code Inist : 002B11A. Création : 09/06/1995.