Objectives-To assess airflow limitation in workers exposed long term to metal dust, the prevalence of pleural plaques in those workers exposed in the past to asbestos, the influence of pleural plaques on lung function, and the possible association with airway disease caused by asbestos.
Methods cross sectional and longitudinal (seven year) survey of 494 long term (mean (SEM) 21 (1) years) workers in a copper refinery was carried out from medical questionnaires, chest radiographs, and forced spirometry.
The prevalence of lifetime nonsmokers was 19%, current smokers 39%, and ex-smokers 42%. The prevalence of chronic obstructive pulmonary diseases (COPD) (forced expiratory volume in one second (FEV1)<80% predicted) was 5%, small airway dysfunction (SAD) (maximal mid-expiratory flow (MMEF)<60% predicted) was 7%, and this did not differ from the control population.
The COPD and SAD were associated with cumulative smoking index but not with the cumulative work years at the plant or with any type of work at the plant.
The mean (SEM) reduction of FEV1 was 20 (7) ml in non-smokers, 26 (4) ml in smokers, and 26 (5) ml in exsmokers (P>0.05).
Mots-clés Pascal : Raffinerie, Cuivre, Industrie métallurgique, Fumée, Poussière, Amiante, Appareil respiratoire pathologie, Exposition professionnelle, Homme, Toxicité, Plaque pleurale, Fonderie, Bronchopneumopathie obstructive, Voie respiratoire, Fibre minérale, Médecine travail
Mots-clés Pascal anglais : Refinery, Copper, Metallurgical industry, Fumes, Dust, Asbestos, Respiratory disease, Occupational exposure, Human, Toxicity, Pleural plate, Foundry, Obstructive pulmonary disease, Respiratory tract, Mineral fiber, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0201444
Code Inist : 002B03L05. Création : 09/06/1995.