This study evaluated mortality among 9796 white male workers at a petroleum-manufacturing plant.
The main purpose was to examine recent patterns in leukemia mortality, for which an increase has been reported in an earlier investigation.
Compared to U.S. white men, the cohort has an excess of leukemia in 1940-1979 (38 observed/23 expected ; standardized mortality ratio=168 ; 95% confidence interval=119-230).
In the 1980s, there was a deficit of leukemia (8 observed/14 expected ; standardized mortality ratio=55 ; 95% confidence interval=24-108).
However, this was balanced by an excess of myelofibrosis and myelodysplasia (4 observed,<1 expected).
These results indicate that any occupational leukemogenic exposures at the plant have been reduced to a point at which they are insufficient to cause leukemia.
Hourly workers also had an excess of deaths from mesothelioma in the 1980s (8 observed, about 2.5 expected), possibly because of exposure to asbestos in the past.
Mots-clés Pascal : Mortalité, Epidémiologie, Homme, Industrie pétrolière, Exposition professionnelle, Leucémie, Médecine travail, Illinois, Etats Unis, Amérique du Nord, Amérique, Hémopathie maligne
Mots-clés Pascal anglais : Mortality, Epidemiology, Human, Oil industry, Occupational exposure, Leukemia, Occupational medicine, Illinois, United States, North America, America, Malignant hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0200656
Code Inist : 002B30A01A2. Création : 09/06/1995.