Physical activity and incidence of diabetes : the Honolulu Heart Program.
Few prospective studies have assessed the relation between physical activity and diabetes.
The authors examined this relation prospectively among 6,815 Japanese-American men in the Honolulu Heart Program who were aged 45-68 years and initially free of diagnosed diabetes in 1965-1968.
A physical activity index was calculated based on time spent per day in different activity levels and a weighting factor correlated with estimated oxygen consumption.
Incidence of clinically recognized diabetes was based on self-reported use of diabetic medication at one of two subsequent examinations.
The age-adjusted 6-year cumulative incidence of diabetes decreased progressively with increasing quintile of physical activity from 73.8 to 34.3 per 1,000 (p<0.0001, trend) in all men and from 53.9 to 21.7 per 1,000 (p<0.0001, trend) among men with a non-fasting glucose level<225 mg/dl one hour after a 50-gm load, the latter group being less likely to have unrecognized diabetes at baseline.
When stratified by tertile of baseline glucose, trends in incidence across physical activity quintiles were statistically significant in the low and middle tertiles but not in the high tertile.
Similar inverse trends were observed for men in the lower four quintiles of body mass index, however, these trends were weaker and not significant for men in the upper quintile of body mass index.
Mots-clés Pascal : Diabète, Epidémiologie, Incidence, Exercice physique, Japonais, Etats Unis, Amérique du Nord, Amérique, Prospective, Asiatique, Homme, Endocrinopathie
Mots-clés Pascal anglais : Diabetes mellitus, Epidemiology, Incidence, Physical exercise, Japanese, United States, North America, America, Prospective, Asiatic, Human, Endocrinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0199673
Code Inist : 002B21E01A. Création : 09/06/1995.