A double-blind controlled Ca supplementation trial win conducted for 6 months in thirty-four 7-year-old Chinese children from Hong-Kong and Jiangmen, China.
The children were randomly allocated to the study group (n 17) or control group (n 17), and a CaCO3 tablet (300 mg Ca) or a placebo tablet win taken daily.
True fractional Ca absorption (TFCA) win evaluated before and after the trial using stable isotopes : 8 mg 44 Ca mixed in 100 g chocolate milk was given after an intravenous injection of 0.75 mg 42Ca.
There was no significant difference in baseline TFCA between the study group (60.6 (SD 11.4)%) and the controls (58.2 (SD 9.0)% ; P=0.55).
Serum 25-hydroxycholecalciferol levels were comparable between the two groups (P=0.71).
After 6 months, TFCA of the study group (55.6 (SD 12.7)%) was significantly lower than that of the controls (64.3 (SD 10.7)% ; P=0.015).
By comparing the inbivibual changes in TFCA after the trial between the two groups there was a non-significant reduction in TFCA (5.03 (SD 12.4)% ; P=0.11, Wilcoxon signed-rank test) in the study group (60.6-55.6%), wherein a significant increase in TFCA (6.17 (SD 7.7)% ; P=0.004, Wilcoxon signed-rank test) win observes in the controls (58.2-64.3%). The differentialin TFCA between the two groups after 6 months win significantly different (P=0.001), and remained signficant after adjustment for baseline dietary intakes, weight and height by multiple-regression analysis (P=0.003).
Mots-clés Pascal : Chine, Asie, Régime alimentaire enrichi, Calcium, Traitement, Adaptation, Absorption, Etat nutritionnel, Cholécalciférol(25-hydroxy), Elément minéral, Nutrition, Alimentation, Enfant, Homme
Mots-clés Pascal anglais : China, Asia, Supplemented diet, Calcium, Treatment, Adaptation, Absorption, Nutritional status, Cholecalciferol(25-hydroxy), Inorganic element, Nutrition, Feeding, Child, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0193665
Code Inist : 002B02N. Création : 09/06/1995.