To compare the costs and effects of two different intervention strategies for the nonpharmacological treatment of hypercholesterolaemia.
Randomized, controlled trial.
Subjects were randomly allocated to one of two intervention models and followed up for 1 year.
Varby Health Centre, a primary care practice located in a suburb of Stockholm.
Subjects with a total serum cholesterol in the range 7.0-7.8 mmol L-1 and no signs of ischaemic heart disease or diabetes mellitus, randomized to a low-intensity (n=35) or medium-intensity (n=41) intervention.
Two strategies were used, one labelled medium-intensity strategy which followed national current guidelines for nonpharmacological treatment of hypercholesterolaemia, the other was a lowintensity strategy.
Total serum cholesterol and intervention costs.
Both intervention strategies resulted in small (mean 3.5%) decreases in total cholesterol with no significant difference between the groups.
The cost per subject in the low-intensity group was SEK 753 and in the medium-intensity group SEK 3614.
Because the effect of the two intervention programmes did not differ, the low-intensity programme is to be preferred from a cost-effectiveness point of view.
Mots-clés Pascal : Hypercholestérolémie, Traitement, Régime alimentaire, Exercice physique, Intensité, Relation, Coût, Efficacité, Soin santé primaire, Homme, Lipide, Cholestérol, Métabolisme pathologie, Hyperlipoprotéinémie
Mots-clés Pascal anglais : Hypercholesterolemia, Treatment, Diet, Physical exercise, Intensity, Relation, Costs, Efficiency, Primary health care, Human, Lipids, Cholesterol, Metabolic diseases, Hyperlipoproteinemia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0192361
Code Inist : 002B26F. Création : 09/06/1995.