Radon at sufficiently high concentrations is known to cause lung cancer among underground miners and in experimental laboratory animals.
Our aim was to determine whether indoor levels of radon are associated with a detectable increase in lung cancer.
Nonsmoking women were selected because they offer the best opportunity to detect radon-related risk while minimizing the potentially confounding influences of cigarette smoking and occupation.
A population-based, case-control study of incident lung cancer was conducted in Missouri.
A total of 538 non-smoking white women diagnosed with lung cancer between 1986 and 1992 and 1183 age-matched control subjects were identified from the Missouri Cancer Registry and from driver's license and Medicare listings, respectively.
Information on lung cancer risk factors was obtained by telephone interview.
Year-long radon measurements were sought in every dwelling occupied for the previous 5-30 years. results : Radon measurements covered 78% of the relevant residential period, and women reported being indoors for 84% of this time.
The time-weighted average radon concentrations were exactly the same for case subjects and control subjects (1.82 pCi/L of air [pCi L-1]). Radon levels greater than 4 pCi L-1 were experienced by 6.5% of the case subjects and 6.8% of the control subjects.
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Facteur risque, Epidémiologie, Incidence, Radon, Concentration, Bâtiment habitation, Analyse risque, Etats Unis, Amérique du Nord, Amérique, Homme, Femelle, Non fumeur, Radioisotope, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Risk factor, Epidemiology, Incidence, Radon, Concentration, Dwelling building, Risk analysis, United States, North America, America, Human, Female, Non smoker, Radioisotope, Respiratory disease, Lung disease, Bronchus disease, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0184016
Code Inist : 002B11A. Création : 09/06/1995.