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  1. Leukodepleted-ABO-identical blood components in the treatment of hematologic malignancies : a cost analysis.

    Article - En anglais

    To assess the effect of ABO-identical, filtration leukodepleted transfusions on resource consumption and costs of care we performed a cohort study in consecutive adult patients admitted for induction therapy of acute myeloid or lymphoid leukemia during 1985-92 (n=120) and consecutive adult patients admitted for autologous bone marrow transplantation for Hodgkin's or non-Hodgkin's lymphoma during 1989-1991 in our university hospital.

    Patients with acute leukemia received either ABO unmatched, unfiltered transfusions (1985-89), ABO identical, unfiltered transfusions (1987-90), or ABO identical, filtered transfusions (1990-92).

    Patients with lymphoma received either ABO unmatched, unfiltered transfusions (1989-90) or ABO identical, filtered transfusions (1990-91).

    Mean platelet transfusion requirements per patient decreased with ABO identical platelets and filtered transfusions : from 143 to 71 units in the transplant setting ; from 146 to 83 in acute leukemia (P<0.05).

    Mean hospital ancillary service charges in 1992 dollars decreased with ABO identicaI platelets and filtered transfusions approximately $14,000 per patient for acute leukemia and $26,000 for for lymphoma.

    Mots-clés Pascal : Leucémie lymphoblastique, Leucémie myéloblastique, Hodgkin maladie, Lymphome non hodgkinien, Transfusion, Thrombocyte, Erythrocyte, Déplétion, Leucocyte, Constituant sang, Traitement induction, Analyse coût, Economie santé, Etats Unis, Amérique du Nord, Amérique, Adulte, Homme, Aigu, Hémopathie maligne, Lymphoprolifératif syndrome, Lymphome

    Mots-clés Pascal anglais : Acute lymphocytic leukemia, Acute myelocytic leukemia, Hodgkin disease, Non Hodgkin lymphoma, Transfusion, Platelet, Red blood cell, Depletion, Leukocyte, Blood product, Induction treatment, Cost analysis, Health economy, United States, North America, America, Adult, Human, Acute, Malignant hemopathy, Lymphoproliferative syndrome, Lymphoma

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0178137

    Code Inist : 002B27D01. Création : 09/06/1995.