Differentiation of benign and malignant adnexal masses : relative value of gray-scale, color Doppler, and spectral Doppler sonography.
The purpose of this study was to evaluate prospectively the relative usefulness of color Doppler, spectral Doppler, and gray-scale sonography in differentiating benign from malignant adrexal masses.
SUBJECTS AND METHODS
A total of 170 adrexal masses in 161 patients were classified prospectively as suggestive of or not suggestive of malignant tumor on the basis of gray-scale morphology, internal flow versus peripheral or no flow, and spectral Doppler pulsatility, as measured by a pulsatility index (PI) threshold of 1.0 and a resistive index (RI) threshold of 0.4. RESULTS.
Surgical pathology revealed 123 benign masses and 46 malignant masses.
One malignant mass was confirmed by cytologic evaluation of ascitic fluid.
On gray-scale analysis, 46 of the 47 malignant masses were classified as suggestive of tumor, and 76 of the 123 benign masses were classified as not suggestive of tumor (sensitivity, 98% ; specificity, 62% ; negative predictive value [NPV], 99% ; and positive predictive value [PPV], 50%). The use of internal color flow as a predictor of malignant tumor yielded a sensitivity of 77%, a specificity of 69%, an NPV of 89%, and a PPV of 49%. The PI and RI values were significantly lower (p<. 0001) in malignant masses than in benign masses, although the values overlapped considerably.
Mots-clés Pascal : Appareil génital pathologie, Appareil génital femelle pathologie, Tumeur bénigne, Tumeur maligne, Diagnostic, Homme, Femelle, Etude expérimentale, Exploration ultrason, Dopplérométrie, Echographie, Annexe utérine, Annexe utérine pathologie, Echelle gris, Analyse spectrale, Couleur, Voie intravaginale, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Genital diseases, Female genital diseases, Benign neoplasm, Malignant tumor, Diagnosis, Human, Female, Experimental study, Sonography, Doppler ultrasound study, Echography, Adnexa uteri, Adnexal diseases, Gray scale, Spectral analysis, Color, Intravaginal administration, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0176397
Code Inist : 002B24C06. Création : 09/06/1995.