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  1. Does intermittent sun exposure cause basal cell carcinoma ? A case-control study in Western Australia.

    Article - En anglais

    Our report deals with the relationship of pattern and timing of sun exposure to basal cell carcinoma (BCC) in a population-based case-control study conducted in Western Australia in 1988.

    The main measure of intermittent exposure was based on the amount of exposure on non-working days relative to that over the whole week.

    Outdoor recreational activities, holidays and sunburn were also considered to be markers of intermittent exposure.

    We observed a statistically significant increase in risk of BCC with increasing proportion of weekly sun exposure obtained at the weekend, especially in late teenage (OR=3.9,95% CI 1.9-7.8 for maximum intermittency of exposure), exposure of the site of skin cancer during holidays (OR=1.9,95% CI 1.1-3.1 for the highest exposure quarter) and sunburn to the site (ORs of 1.8 for 3-10 and 1.5 for 11+sunburns in a lifetime).

    Risk of BCC increased substantially with increasing intermittency in poor tanners but not at all in good tanners.

    Our data suggest that a particular amount of sun exposure delivered in infrequent, probably intense increments will increase risk of BCC more than a similar dose delivered more continuously over the same total period of time.

    Mots-clés Pascal : Epithélioma basocellulaire, Facteur risque, Epidémiologie, Rayonnement solaire, Rayonnement UV, Intermittence, Ouest, Australie, Océanie, Homme, Peau pathologie, Tumeur maligne, Etude cas témoin

    Mots-clés Pascal anglais : Basal cell carcinoma, Risk factor, Epidemiology, Solar radiation, Ultraviolet radiation, Intermittency, West, Australia, Oceania, Human, Skin disease, Malignant tumor, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0167815

    Code Inist : 002B08A. Création : 09/06/1995.