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  1. Do physical and chemical working conditions explain the association of social class with ischaemic heart disease ?

    Article - En anglais

    The aim of this study was to examine whether physical and chemical working conditions explain the association of social class with ischaemic heart disease (IHD).

    We investigated the issue in a cohort of 2974 males aged 53-75 years (mean 63) free from overt cardiovascular disease.

    Potential confounders included were : alcohol consumption, physical activity, tobacco smoking, serum cotinine, serum lipids, serum selenium, body mass index, blood pressure, hypertension, social class, and retirement status.

    During the follow-up period (1985-1986 to 31 December 1991), 184 men (6.2%) had a first IHD event ; 44 events were fatal.

    Compared to higher social classes (classes I, II and III), lower classes (classes IV and V) had a significantly increased risk of IHD (P<0.05) ; the age-adjusted relative risk (RR) with 95% confidence limits was 1.44 (1.06-1.95), P=0.02.

    Men who had been occupationally long-term exposed (=5 years) to either soldering fumes or organic solvents had a significantly higher risk of IHD than unexposed : RRs were 2.1 and 1.7, respectively.

    After adjustment for all the above potential confounders and including also these two occupational factors, the RR of low social classes was reduced to a non-significant 1.24 (0.87-1.76), P=0.24, i.e. by 45%. Adjusting for non-occupational factors only reduced the RR from 1.44 to 1.38 (1.0-1.90), P=0.05, i.e. by about 14%.

    Mots-clés Pascal : Cardiopathie coronaire, Classe sociale, Condition travail, Exposition professionnelle, Fumée, Soudure, Solvant organique, Facteur risque, Homme, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Coronary heart disease, Social class, Working condition, Occupational exposure, Fumes, Weld, Organic solvent, Risk factor, Human, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0167773

    Code Inist : 002B12A03. Création : 09/06/1995.