The aim of this study was to examine whether physical and chemical working conditions explain the association of social class with ischaemic heart disease (IHD).
We investigated the issue in a cohort of 2974 males aged 53-75 years (mean 63) free from overt cardiovascular disease.
Potential confounders included were : alcohol consumption, physical activity, tobacco smoking, serum cotinine, serum lipids, serum selenium, body mass index, blood pressure, hypertension, social class, and retirement status.
During the follow-up period (1985-1986 to 31 December 1991), 184 men (6.2%) had a first IHD event ; 44 events were fatal.
Compared to higher social classes (classes I, II and III), lower classes (classes IV and V) had a significantly increased risk of IHD (P<0.05) ; the age-adjusted relative risk (RR) with 95% confidence limits was 1.44 (1.06-1.95), P=0.02.
Men who had been occupationally long-term exposed (=5 years) to either soldering fumes or organic solvents had a significantly higher risk of IHD than unexposed : RRs were 2.1 and 1.7, respectively.
After adjustment for all the above potential confounders and including also these two occupational factors, the RR of low social classes was reduced to a non-significant 1.24 (0.87-1.76), P=0.24, i.e. by 45%. Adjusting for non-occupational factors only reduced the RR from 1.44 to 1.38 (1.0-1.90), P=0.05, i.e. by about 14%.
Mots-clés Pascal : Cardiopathie coronaire, Classe sociale, Condition travail, Exposition professionnelle, Fumée, Soudure, Solvant organique, Facteur risque, Homme, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Coronary heart disease, Social class, Working condition, Occupational exposure, Fumes, Weld, Organic solvent, Risk factor, Human, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0167773
Code Inist : 002B12A03. Création : 09/06/1995.