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  1. Lung adenocarcinoma and indicators of asbestos exposure.

    Article - En anglais

    A case-control study was carried out on 145 male lung-cancer patients diagnosed at autopsy and 178 controls, in order to investigate the relationship between asbestos exposure and the cell type of pulmonary carcinoma.

    Adenocarcinomas (AD) were individually matched with other cell types and with controls.

    The relative risk (RR) of developing AD in relation with lung asbestos body (AB) content as the exposure indicator was calculated by using logistic-regression analysis for matched sets.

    Two cutoff levels, 1,000 and 10,000 asbestos bodies per gram dry weight (AB/gdw), were used in the analysis.

    In addition, AB counts were treated as a continuous variable (log AB+1).

    A significant association was found between AD and asbestos exposure, using levels and logarithmic transformation.

    However, an association of asbestos exposure with cell types other than AD could not be ruled out.

    Mots-clés Pascal : Epithélioma glandulaire, Bronchopulmonaire, Epithélioma, Epidémiologie, Facteur risque, Exposition, Amiante, Italie, Europe, Nord ouest, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Tumeur maligne, Type histologique

    Mots-clés Pascal anglais : Adenocarcinoma, Bronchopulmonary, Carcinoma, Epidemiology, Risk factor, Exposure, Asbestos, Italy, Europe, Northwest, Human, Respiratory disease, Lung disease, Bronchus disease, Malignant tumor, Histological type

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0166194

    Code Inist : 002B11A. Création : 09/06/1995.