Objective To evaluate the effect of changed cervical screening policies on a steady population with low migratory tendencies.
Setting Dundee and Angus, Scotland.
Subjects All women who developed cervical carcinoma between 1957 and 1992.
Main outcome measures The incidence of and mortality from cervical cancer after the introduction of organised cervical screening in 1962, according to age, stage, histology and screening history.
Results The initial fall in incidence of cervical cancer seen in women between 3 5 and 54 years after the introduction of cervical screening was not sustained during the last 10 years of our study and appears to have been transferred to women aged 55 years and older instead.
After 1976 an increase in the incidence of cervical cancer was seen in women under 35 years.
The reduction in mortality from cervical cancer appears to have reached a plateau since 1976.
No effect of cervical screening was seen on the incidence of adenocarcinoma of the cervix.
Conclusions The effect of changed cervical screening policies has been shown for a small population for a period of 35 years.
The incidence of the higher stages of squamous cervical cancer continues to fall.
The increase in incidence of cervical cancer in women under 35 years confirms similar trends seen in other countries.
A background mortality rate refractory to further intensification of screening appears to have been reached.
Mots-clés Pascal : Dysplasie col utérus, Epithélioma, Col utérus, Dépistage, Surveillance, Méthode, Immunohistochimie, Ecosse, Grande Bretagne, Royaume Uni, Europe, Etude longitudinale, Homme, Lésion précancéreuse, Appareil génital femelle pathologie, Col utérus pathologie, Tumeur maligne, Anatomopathologie
Mots-clés Pascal anglais : Cervical dysplasia, Carcinoma, Uterine cervix, Medical screening, Surveillance, Method, Immunohistochemistry, Scotland, Great Britain, United Kingdom, Europe, Follow up study, Human, Premalignant lesion, Female genital diseases, Uterine cervix diseases, Malignant tumor, Pathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0162528
Code Inist : 002B20C02. Création : 09/06/1995.