AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL, vol. 56, n° 2, 1995, pages 158-170, 16 réf., ISSN 0002-8894, USA
TEPPER (J.S.), MOSER (V.C.), COSTA (D.L.), MASON (M.A.), ROACHE (N.), ZHISHI (G.U.O.), DYER (R.S.)
ManTech Environmental Technology Inc. Research Triangle Park NC. USA
This study investigated findings that the off-gassing of certain carpets caused sensory and pulmonary irritation, changes in neurobehavioral signs, and death in exposed mice.
Two standard test method measures - one for estimating sensory irritancy (ASTM-E981-84), the other for evaluating the neurotoxic potential of chemicals (functional observational battery) - were coupled with a postmortem assessment to ascertain the mechanism of toxicity.
The postmortem evaluation included measurements of hemoglobin, serum clinical chemistries, blood and lung lavage white cell counts and differential, organ weights, and a gross necropsy with a microscopic evaluation of all major organs.
The study evaluated three treatment groups composed of two preheated carpet emission exposures and one preheated air-control exposure.
No toxic effects were associated with exposure to the off-gassing of the two tested carpets.
Clinical chemistry and histopathological alterations were observed with exposure to either filter-air or carpet when compared to nonexposed unrestrained control mice, indicating that the exposure procedure caused significant effects unrelated to carpet emissions.
A detailed chemical and microbial evaluation of the carpets and carpet emissions showed volatile organic compounds, pesticide residues, and microbiological flora, but at insufficient quantities to result in acute toxicity.
Mots-clés BDSP : Pesticide, Microorganisme, Homme, Animal, Inhalation, Appareillage
Mots-clés Pascal : Tapis, Composé volatil, Pesticide, Résidu, Flore associée, Microorganisme, Toxicité, Homme, Souris, Rodentia, Mammalia, Vertebrata, Animal, Inhalation, Chambre observation, Appareillage, Méthode étude
Mots-clés Pascal anglais : Carpet, Volatile compound, Pesticides, Residue, Associated flora, Microorganism, Toxicity, Human, Mouse, Rodentia, Mammalia, Vertebrata, Animal, Inhalation, Exposure chamber, Instrumentation, Investigation method
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0149552
Code Inist : 002B03L03. Création : 09/06/1995.