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  1. Toxicological and chemical evaluation of emissions from carpet samples.

    Article - En anglais

    This study investigated findings that the off-gassing of certain carpets caused sensory and pulmonary irritation, changes in neurobehavioral signs, and death in exposed mice.

    Two standard test method measures - one for estimating sensory irritancy (ASTM-E981-84), the other for evaluating the neurotoxic potential of chemicals (functional observational battery) - were coupled with a postmortem assessment to ascertain the mechanism of toxicity.

    The postmortem evaluation included measurements of hemoglobin, serum clinical chemistries, blood and lung lavage white cell counts and differential, organ weights, and a gross necropsy with a microscopic evaluation of all major organs.

    The study evaluated three treatment groups composed of two preheated carpet emission exposures and one preheated air-control exposure.

    No toxic effects were associated with exposure to the off-gassing of the two tested carpets.

    Clinical chemistry and histopathological alterations were observed with exposure to either filter-air or carpet when compared to nonexposed unrestrained control mice, indicating that the exposure procedure caused significant effects unrelated to carpet emissions.

    A detailed chemical and microbial evaluation of the carpets and carpet emissions showed volatile organic compounds, pesticide residues, and microbiological flora, but at insufficient quantities to result in acute toxicity.

    Mots-clés Pascal : Tapis, Composé volatil, Pesticide, Résidu, Flore associée, Microorganisme, Toxicité, Homme, Souris, Rodentia, Mammalia, Vertebrata, Animal, Inhalation, Chambre observation, Appareillage, Méthode étude

    Mots-clés Pascal anglais : Carpet, Volatile compound, Pesticides, Residue, Associated flora, Microorganism, Toxicity, Human, Mouse, Rodentia, Mammalia, Vertebrata, Animal, Inhalation, Exposure chamber, Instrumentation, Investigation method

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0149552

    Code Inist : 002B03L03. Création : 09/06/1995.