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  1. An investigation of the relationship between antioxidant vitamin intake and coronary heart disease in men and women using logistic regression analysis.

    Article - En anglais

    Antioxidant vitamin intake (C, E and carotene) is assessed from a food frequency questionnaire applied to 10,359 middle-aged men and women participating in the Scottish Heart Health Study.

    Logistic regression analysis is then used to quantify the relationship between antioxidant vitamin consumption and prevalent coronary heart disease (CHD), analysing diagnosed and undiagnosed cases separately.

    For men, there is a protective effect of all three antioxidants, before and after adjustment for a comprehensive set of confounding variables.

    For women the picture is less clear, only vitamin C is negatively associated with CHD, but the effect is removed by adjustment.

    The logistic regression model is also used to determine classification rules for deciding whether or not an individual has CHD.

    The classification error rates using the antioxidants are found to be very similar to those found using smoking, blood pressure and serum total cholesterol as classification variables.

    Significant interactions are found for the antioxidants with smoking, cholesterol and age.

    It is concluded that antioxidant vitamin intake protects against CHD for men.

    Logistic regression analysis is compared with discriminant analysis, and is found to have important advantages as an epidemiological tool.

    Mots-clés Pascal : Cardiopathie coronaire, Epidémiologie, Homme, Consommation alimentaire, Comportement alimentaire, Régime alimentaire enrichi, Vitamine, Antioxydant, Sexe, Ecosse, Grande Bretagne, Royaume Uni, Europe, Régression logistique, Analyse statistique, Prévention, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Coronary heart disease, Epidemiology, Human, Food intake, Feeding behavior, Supplemented diet, Vitamin, Antioxidant, Sex, Scotland, Great Britain, United Kingdom, Europe, Logistic regression, Statistical analysis, Prevention, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0149213

    Code Inist : 002B12A03. Création : 09/06/1995.