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  1. Blood toluene as a biological index of environmental toluene exposure in the "normal" population and in occupationally exposed workers immediately after exposure and 16 hours later.

    Article - En anglais

    Blood toluene was measured in a group of 100 workers occupationally exposed to a mean 8-h environmental toluene concentration of 128 mug/l (34 ppm), and in a group of 269 « normal » subjects without occupational exposure to toluene.

    The mean blood toluene of the workers at the end of the shift and the following morning, after 16 h, was 457 and 38 mug/l, respectively.

    The normal subjects had a blood toluene level of 1.1 mug/l. On the basis of the highly significant correlation between blood toluene and occupational exposure, it can be calculated that environmental toluene exposure of 188 and 377 mug/l (50 and 100 ppm) gives end-of-shift blood toluene levels of 690 and 1390 mug/l, respectively.

    The corresponding blood toluene levels on the following morning are 50 and 100 mug/l, respectively.

    Mots-clés Pascal : Toluène, Polluant, Environnement, Exposition professionnelle, Surveillance biologique, Homme, Relation dose métabolisme, Relation temps métabolisme, Sang, Médecine travail, Solvant organique

    Mots-clés Pascal anglais : Toluene, Pollutant, Environment, Occupational exposure, Biological monitoring, Human, Dose metabolism relationship, Time metabolism relation, Blood, Occupational medicine, Organic solvent

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0143760

    Code Inist : 002B03L04. Création : 09/06/1995.