Objectives-To determine whether the respiratory symptoms and decrements in lung function found in manufacturers of ceramic fibres are related to exposure to the respirable fibre or inspirable mass constituents of the air in the working environment.
Methods-Cross sectional survey of all current European primary producers of ceramic fibre was carried out, with measurement of exposure to respiratory fibres by personal samplers that measured inspirable and total mass, together with a health survey with an expanded respiratory questionnaire and standardised measurement of lung function.
Odds ratios were calculated for symptoms and current exposure by multiple logistic regression, and multiple linear regression coefficients for lung Unction related to cumulative exposures controlled for the effects of respirable fibre and inspirable mass separately and together.
Significant effects of current exposure to both inspirable dust and respirable fibres were related to dry cough, stuff nose, eye and skin irritation and breathlessness.
The decrements found in smokers and to some extent in exsmokers in forced expiratory volume in one second and forced expiratory flow from 25% to 75% of expiratory volume, seem to be related to the respirable fibres rather than the inspirable mass constituents of the environment.
Conclusions-Current symptoms were related to both current exposure to inspirable dust and respirable fibre.
Mots-clés Pascal : Fibre minérale, Fibre artificielle, Fibre céramique, Industrie, Exposition professionnelle, Toxicité, Poussière, Appareil respiratoire pathologie, Homme, Fonction respiratoire, Epidémiologie, Europe, Etude multicentrique, Médecine travail
Mots-clés Pascal anglais : Mineral fiber, Artificial fiber, Ceramic fiber, Industry, Occupational exposure, Toxicity, Dust, Respiratory disease, Human, Lung function, Epidemiology, Europe, Multicenter study, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0143598
Code Inist : 002B03L03. Création : 09/06/1995.