Objectives-To study the relation between occupational exposure to ceramic fibres during manufacture and respiratory health.
Methods-The respiratory health of 628 current employees in the manufacture of ceramic fibres in seven European plants in three countries was studied with a questionnaire, lung function tests, and chest radiography.
Simultaneous plant hygiene surveys measured subjects'current exposure to airborne ceramic fibres from personal samples with optical microscopy fibre counts.
The measured exposures were combined with occupational histories to derive estimates of each subject's cumulative exposure to respirable fibres.
Symptoms were related to current and cumulative exposure to ceramic fibres and lung function and findings from chest radiographs were related to cumulative exposure.
The mean duration of employment was 10.2 years and mean (range) cumulative exposure was 3.84 (0-22.94) (f. ml-1. y).
Eye and skin symptoms were frequent in all plants and increased significantly, as did breathlessness and wheeze, with increasing current exposure.
Dry cough and stuffy nose were less common in the least exposed group but did not increase with increasing exposure.
After adjustment, there was a significant decrease in both forced expiratory volume in one second (FEV1) and forced midexpiratory flow related to cumulative exposure in current smokers (P<0.05) AND IN FEV1 in ex-smokers (P<0.05), Small opacities were found in 13% of the chest radiographs.
Mots-clés Pascal : Industrie, Fibre céramique, Fibre artificielle, Exposition professionnelle, Toxicité, Homme, Appareil respiratoire pathologie, Etude multicentrique, Epidémiologie, Fibre minérale, Irritation, Royaume Uni, Europe, France, Allemagne, Médecine travail
Mots-clés Pascal anglais : Industry, Ceramic fiber, Artificial fiber, Occupational exposure, Toxicity, Human, Respiratory disease, Multicenter study, Epidemiology, Mineral fiber, Irritation, United Kingdom, Europe, France, Germany, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0143597
Code Inist : 002B03L03. Création : 09/06/1995.