Comparison of cost-effectiveness and utility of exercise ECG, single photon emission computed tomogrpahy, positron emission tomography, and coronary angiography for diagnosis of coronary artery disease.
Background To compare cost-effectiveness and utility of four clinical algorithms to diagnose obstructive coronary atherosclerotic heart disease (CAD), we compared exercise ECG (ExECG), stress single photon emission computed tomography (SPECT), positron emission tomography (PET), and coronary angiography.
Methods and Results Published data and a straightforward mathematical model based on Bayes'theorem were used to compare strategies.
Effectiveness was defined as the number of patients with diagnosed CAD, and utility was defined as the clinical outcome, ie, the number of quality-adjusted life years (QALY) extended by therapy after the diagnosis of CAD.
Our model used published values for costs, accuracy, and complication rates of tests.
Analysis of the model indicates the following results.
Mots-clés Pascal : Cardiopathie coronaire, Analyse coût efficacité, Economie santé, Electrocardiographie, Epreuve effort, Tomoscintigraphie, Photon, Positon, Coronarographie, Etude comparative, Exploration, Homme, Appareil circulatoire pathologie, Electrodiagnostic, Exploration radioisotopique, Radiodiagnostic
Mots-clés Pascal anglais : Coronary heart disease, Cost efficiency analysis, Health economy, Electrocardiography, Exercise tolerance test, Emission tomography, Photon, Positron, Coronary arteriography, Comparative study, Exploration, Human, Cardiovascular disease, Electrodiagnosis, Radionuclide study, Radiodiagnosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0139533
Code Inist : 002B12A03. Création : 09/06/1995.