Reported prevalence rates for protein C (PC) deficiency in the population at large have varied widely.
The differences presumably reflect the existence of an apparently high number of clinically recessive forms of the deficiency.
In an attempt to document more precisely the prevalence of PC deficiency in the healthy population we have measured PC activity in just under 10,000 blood donors in the West of Scotland.
Aftenepeat testing of donors with low results and then further observation and selection, 32 donors were identified who had individual mean PC activities below the age-and gender-specific study reference range.
Mots-clés Pascal : Déficit, Protéine C, Prévalence, Epidémiologie, Ecosse, Grande Bretagne, Royaume Uni, Europe, Ouest, Etude cohorte, Homme, Hémopathie, Coagulopathie, Maladie héréditaire
Mots-clés Pascal anglais : Deficiency, Protein C, Prevalence, Epidemiology, Scotland, Great Britain, United Kingdom, Europe, West, Cohort study, Human, Hemopathy, Coagulopathy, Genetic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0131154
Code Inist : 002B19C. Création : 09/06/1995.