To explore associations between epxosure to asbestos cement dust and radiographic findings in lung parenchyma and pleura.
Methods-Radiographs from 174 blue collar workers and 29 white collar workers from an asbestos cement plant formed one part of the study.
Progression of small opacities was further studied in those 124 blue collar workers, for whom two radiographs taken after the end of employment were available.
The median readings from five readers who used thef full ILO 1980 classification were used.
As exposure indices, time since start of employment, duration of employment, cumulative exposure, and average intensity of asbestos exposure were used.
The influence of age and smoking was also considered in multiple logistic regression analyses.
Small opacities (profusion =1/0) were closely correlated with time related epxosure variables, and showed weaker association with intensity based exposure variables.
The odds ratio (OR) for small opacities was equal to 2.8 (90% CI 1.2,6.7) in the>30 f (fibre) - y/ml group, compared with those in the 0.10 f-y/ml group.
Progression of at least two minor ILO categories after the end of employment was seen in 20%. Also, pleural kickening was closely related to time.
By contrast, costophrenic angle obliterations were not associated with the time related variables, but closely associated with the intensity of asbestos epxosure, and tended to occur during employment.
Mots-clés Pascal : Cimenterie, Amiante, Poussière, Exposition professionnelle, Homme, Poumon pathologie, Exploration radiologique, Relation temps réponse, Médecine travail, Parenchyme, Plèvre, Toxicité, Fibre minérale, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Cement plant, Asbestos, Dust, Occupational exposure, Human, Lung disease, Radiologic investigation, Time response relation, Occupational medicine, Parenchyma, Pleura, Toxicity, Mineral fiber, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0118500
Code Inist : 002B03L03. Création : 09/06/1995.