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  1. High-risk studies are influenced by indirect range restriction.

    Article - En anglais

    High-risk studies select subjects who are at high risk for existing or future disease.

    Therefore, the range of disease is restricted in high-risk studies.

    This paper shows that high-risk studies are vulnerable to a particular type of range restriction referred to as indirect range restriction.

    A simulation study is used to illustrate the effects of indirect range restriction on high-risk studies.

    The results suggest that indirect range restriciton can have a substantial impact on the results of high-risk studies.

    Mots-clés Pascal : Méthodologie, Méthode statistique, Facteur risque, Cardiopathie coronaire, Comportement type A, Personnalité, Epidémiologie, Homme

    Mots-clés Pascal anglais : Methodology, Statistical method, Risk factor, Coronary heart disease, Type A behavior, Personality, Epidemiology, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0091338

    Code Inist : 002A26N06. Création : 09/06/1995.