Between 1920 and 1965, radiation treatment to the ovaries and/or pituitary gland was used for refractory hormonal infertility and amenorrhoea.
The potential carcinogenic effects of hormonal infertility, as well as exposure to relatively low doses of ovarian and pituitary radiation can be studied among patients receiving these treatments.
A cohort of 816 patients treated between 1925 and 1961 was identified from the medical records of a New York City radiologist.
The mortality experience for 84% of these women was determined and radiation doses for individual patients were estimated.
Doses were, on average, 87,64,54, and 29 cGy to the ovary, brain, colon, and active bone marrow, respectively.
Mots-clés Pascal : Radiothérapie, Rayon X, Toxicité, Aménorrhée, Stérilité, Homme, Femelle, Mortalité, Epidémiologie, Carcinogène, Etats Unis, Amérique du Nord, Amérique, Appareil génital femelle pathologie, Cycle menstruel pathologie
Mots-clés Pascal anglais : Radiotherapy, X ray, Toxicity, Amenorrhea, Sterility, Human, Female, Mortality, Epidemiology, Carcinogen, United States, North America, America, Female genital diseases, Menstruation disorders
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0087546
Code Inist : 002B26L. Création : 09/06/1995.