The Nottingham prognostic index applied to 9,149 patients from the studies of the danish breast cancer cooperative group (DBCG).
In primary, operable breast cancer, the Nottingham Prognostic Index (NPI) based on tumour size, lymphnode stage and histological grade can identify three prognostic groups (PGs) with 10-year survival rates of 83%, 52%, and 13%. With the aim of defining a subset of patients having so good prognosis that adjuvant therapy can be withhold, the NPI was applied to a Danish population-based study group comprising 9,149 patients.
As opposed to the British study, we used conventional axillary lymph-node staging.
Histological grading was in both studies done by means of a similar slight modification of the Bloom and Richardson procedure, but in the Danish study only ductal carcinomas were graded.
Mots-clés Pascal : Pronostic, Danemark, Europe, Homme, Tumeur maligne, Glande mammaire, Grade histologique, Ganglion lymphatique, Taille, Survie, Glande mammaire pathologie
Mots-clés Pascal anglais : Prognosis, Denmark, Europe, Human, Malignant tumor, Mammary gland, Histological grading, Lymph node, Size, Survival, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0081227
Code Inist : 002B20E02. Création : 09/06/1995.