In primary, operable breast cancer, the Nottingham Prognostic Index (NPI) based on tumour size, lymphnode stage and histological grade can identify three prognostic groups (PGs) with 10-year survival rates of 83%, 52%, and 13%. With the aim of defining a subset of patients having so good prognosis that adjuvant therapy can be withhold, the NPI was applied to a Danish population-based study group comprising 9,149 patients.
As opposed to the British study, we used conventional axillary lymph-node staging.
Histological grading was in both studies done by means of a similar slight modification of the Bloom and Richardson procedure, but in the Danish study only ductal carcinomas were graded.
Mots-clés Pascal : Pronostic, Danemark, Europe, Homme, Tumeur maligne, Glande mammaire, Grade histologique, Ganglion lymphatique, Taille, Survie, Glande mammaire pathologie
Mots-clés Pascal anglais : Prognosis, Denmark, Europe, Human, Malignant tumor, Mammary gland, Histological grading, Lymph node, Size, Survival, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0081227
Code Inist : 002B20E02. Création : 09/06/1995.