A population-based register of all autosomal trisomies diagnosed in Scotland was established in 1989.
Data were provided by all cytogenetic service laboratories, and included karyotype, date and place of outcome, indication for analysis, maternal age and place of residence.
The Register includes all foetuses diagnosed prenatally and all cytogenetically-confirmed live-and still-births with autosomal trisomy, including partial, mosaic and familial cases.
In the 2 years 1989-90,76 prenatal and 147 postnatal diagnoses were notified.
For Down syndrome karyotypes the estimated rate, assuming no terminations and after adjusting for spontaneous foetal losses following diagnosis, was 1.23 per 1000 livebirths.
Mots-clés Pascal : Trisomie, Aneuploïdie, Aberration chromosomique, Ecosse, Grande Bretagne, Royaume Uni, Europe, Epidémiologie, Homme
Mots-clés Pascal anglais : Trisomy, Aneuploidy, Chromosomal aberration, Scotland, Great Britain, United Kingdom, Europe, Epidemiology, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0065530
Code Inist : 002B23B. Création : 09/06/1995.