Urinary mandelic acid and hemoglobin adducts in fiberglass-reinforced plastics workers exposed to styrene.
A field study was undertaken to investigate the effects of occupational styrene exposure on mandelic acid excretion and the formation of styrene-7,8-oxide hemoglobin adducts.
Especially the sensitivity of a gas chromatography-mass spectrometry method for determining hemoglobin adducts was evaluated.
Over a four-week period, each individual of a group of 52 fiberglass-reinforced plastics workers was monitored once a week by the simultaneous measurement of styrene in the air and urinary postshift mandelic acid.
In addition mandelic acid and hemoglobin adducts were monitored in a group of 24 unexposed referents.
Mots-clés Pascal : Styrène, Industrie matière plastique, Plastique renforcé fibre, Exposition professionnelle, Homme, Adduit moléculaire, Métabolite, Surveillance biologique, Urine, Sang, Médecine travail
Mots-clés Pascal anglais : Styrene, Plastics industry, Fibre reinforced plastics, Occupational exposure, Human, Molecular adduct, Metabolite, Biological monitoring, Urine, Blood, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0053404
Code Inist : 002B03L06. Création : 09/06/1995.