Increased risk of neuroectodermal tumors and stomach cancer in relatives of patients with Ewing's sarcoma family of tumors.
Previous studies of the genetic epidemiology of Ewing's sarcoma have shown neither an increased incidence nor a distinct pattern of cancers in family members of Ewing's sarcoma patients.
Because of a new biologic and cytogenetic classification of Ewing's sarcoma family of tumors, we wanted to reinvestigate the incidence and distribution of cancers in relatives of probands with Ewing's sarcoma family of tumors.
Patients treated at the Pediatric Branch and the Radiation Oncology Branch of the National Cancer Institute between 1965 and December 1992, or their next of kin, were asked to complete a questionnaire on the history of cancer in all first-and second-degree relatives.
Mots-clés Pascal : Tumeur maligne, Estomac, Facteur risque, Tumeur neuroectodermique, Epidémiologie, Réticulosarcome Ewing, Parent, Homme, Os, Estomac pathologie, Appareil digestif pathologie, Système ostéoarticulaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Stomach, Risk factor, Neuroectodermal tumor, Epidemiology, Ewing sarcoma, Parent, Human, Bone, Gastric disease, Digestive diseases, Diseases of the osteoarticular system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0052895
Code Inist : 002B13B01. Création : 09/06/1995.