Occupational and environmental lead exposure has been associated with significant impairment in renal function.
The authors studied the cross-sectional relation between creatinine clearance and blood lead concentration in a population of 744 men participating in the Normative Aging Study of the Department of Veterans Affairs between July 1988 and April 1991.
These men, aged 43-90 years, were recruited from communities in the Greater Boston, Massachusetts, area and were selected without regard to lead exposure.
The mean values for blood lead concentration and creatinine clearance rate were 8.1 mug/dl (standard deviation, 3.9 mug/dl) and 88.2 ml/minute (standard deviation, 22.0 ml/minute), respectively.
Mots-clés Pascal : Plomb, Métal lourd, Toxicité, Homme, Fonction rénale, Créatinine, Rein pathologie, Epidémiologie, Massachusetts, Etats Unis, Amérique du Nord, Amérique, Relation concentration activité, Polluant, Environnement, Appareil urinaire pathologie
Mots-clés Pascal anglais : Lead, Heavy metal, Toxicity, Human, Renal function, Creatinine, Renal disease, Epidemiology, Massachusetts, United States, North America, America, Activity concentration relation, Pollutant, Environment, Urinary system disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0043878
Code Inist : 002B03M01. Création : 09/06/1995.