To evaluate the incidence and prevalence of hemophilia in Italy and the impact of HIV infection on the Italian hemophiliac population, data from a computerized national registry of patients from 95% of the hemophilia care centers in Italy were analyzed.
A total of 4643 patients were included in the registry.
The prevalence of hemophilia A was 8.2 per 100,000 males, with no significant regional differences ; for hemophilia B the corresponding figure was 1.5 per 100,000.
Temporal trends in hemophilia incidence suggest that the diagnosis of mild and moderate hemophilia has improved.
The overall HIV prevalence was 26% and was significantly (p<0.001) higher in patients with hemophilia B (47.1%) compared to those with hemophilia A (26.8%) or other diseases (16.5%).
Mots-clés Pascal : Hémophilie, Epidémiologie, Association morbide, SIDA, Virose, Infection, Homme, Italie, Europe, Registre, Sérologie, Prévalence, Incidence, Hémopathie, Coagulopathie, Maladie héréditaire, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Hemophilia, Epidemiology, Concomitant disease, AIDS, Viral disease, Infection, Human, Italy, Europe, Register, Serology, Prevalence, Incidence, Hemopathy, Coagulopathy, Genetic disease, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0037286
Code Inist : 002B19C. Création : 09/06/1995.