Epidemiology of hemophilia and of HIV infection in Italy.
To evaluate the incidence and prevalence of hemophilia in Italy and the impact of HIV infection on the Italian hemophiliac population, data from a computerized national registry of patients from 95% of the hemophilia care centers in Italy were analyzed.
A total of 4643 patients were included in the registry.
The prevalence of hemophilia A was 8.2 per 100,000 males, with no significant regional differences ; for hemophilia B the corresponding figure was 1.5 per 100,000.
Temporal trends in hemophilia incidence suggest that the diagnosis of mild and moderate hemophilia has improved.
The overall HIV prevalence was 26% and was significantly (p<0.001) higher in patients with hemophilia B (47.1%) compared to those with hemophilia A (26.8%) or other diseases (16.5%).
Mots-clés Pascal : Hémophilie, Epidémiologie, Association morbide, SIDA, Virose, Infection, Homme, Italie, Europe, Registre, Sérologie, Prévalence, Incidence, Hémopathie, Coagulopathie, Maladie héréditaire, Immunopathologie, Immunodéficit
Mots-clés Pascal anglais : Hemophilia, Epidemiology, Concomitant disease, AIDS, Viral disease, Infection, Human, Italy, Europe, Register, Serology, Prevalence, Incidence, Hemopathy, Coagulopathy, Genetic disease, Immunopathology, Immune deficiency
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 95-0037286
Code Inist : 002B19C. Création : 09/06/1995.