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  1. Safety and cost-effectiveness of solvent-detergent-treated plasma : in search of a zero-risk blood supply.

    Article - En anglais


    - To determine the public health and economic implications of solvent-detergent-treated frozen plasma (SD FP).

    While this processing technique nearly eliminates the risk of transmitting lipid-enveloped viruses (hepatitis B and C and human immunodeficiency virus), it has associated costs and, because it requires pooling many plasma units, may increase risks of nonenveloped virus transmission.


    - A previously published Markov decision analysis model was modified to assess transfusion-related outcomes in hypothetical cohorts of plasma recipients.

    In-hospital mortality and other characteristics were determined in 61 patients receiving plasma transfusions at a medium-sized tertiary care center to provide data for the model.

    Other parameters were obtained from the medical literature.

    Mots-clés Pascal : Coût, Efficacité, Test sécurité, Plasma sanguin, Transmission, SIDA, Virose, Infection, Hépatite virale B, Hépatite virale, Homme, Hémopathie, Maladie sexuellement transmissible, Immunopathologie, Foie pathologie, Appareil digestif pathologie

    Mots-clés Pascal anglais : Costs, Efficiency, Safety test, Blood plasma, Transmission, AIDS, Viral disease, Infection, Viral hepatitis B, Viral hepatitis, Human, Hemopathy, Sexually transmitted disease, Immunopathology, Hepatic disease, Digestive diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 95-0022064

    Code Inist : 002B06D01. Création : 09/06/1995.